|First Appearance||"The Nose Job"|
|Portrayed By||Tawny Kitaen|
Isabel is a very beautiful woman whom Jerry is very attracted to physically, but finds her repulsive mentally. As Jerry describes it, "it's like [his] brain is facing [his] penis in a chess game." Jerry decides he can't see her anymore so he begs Kramer to tear up her phone number so he can no longer get in touch with her. However, this doesn't last long, and soon after Jerry desperately begs Kramer to give him the number back. Kramer does so, giving Jerry back the scraps of paper, and Jerry frantically tries to put the pieces back together to get her number back. Jerry gets back together with Isabel but while reading a moronic script with her, Jerry decides to end it once and for all.